Article: Guillain-Barre syndrome in children

Guillain-Barré syndrome is an acquired, autoimmune-mediated radiculopolyneuropathy characterized by an ascending progressive motor weakness and areflexia. Although weakness is the hallmark symptom, differing presentations in children, as opposed to adults, can include predominant symptoms of gait ataxia or pain and a higher incidence of cranial nerve abnormalities. Regional differences in presentation are observed, with demyelinating subtypes more prevalent in Western countries, such as the United States, and axonal subtypes more prevalent in Asia and in Mexico. The most significant complication is the need for respiratory support, which is reported in 10% to 28% of children.

In this recently updated article, Dr. David Hsieh of the Uniformed Services University of the Health Sciences and The University of Texas Health Science Center at San Antonio provides updates on the association of mycoplasma pneumonia with Guillain-Barre syndrome.

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