Vol. 3 No. 1 April 2017          
Upcoming Events

4/13 - CHHE and CMI Joint Seminar - Adriann Beltran, UNC "Genome Editing and Stem Cell Engineering for Disease Modeling"
3:30 pm - 4:30 pm, Toxicology Building Auditorium

4/19 - CHHE Comparative Pathology Core - New RNA ISH Technology Product Info. Seminar
"Current state-of-the-art tissue-based RNA analysis with RNAscope Technology"
12:00 pm - 1:00 pm, Toxicology Building Auditorium

4/25 - CHHE and Toxicology Co-sponsored Seminar: Rick Woychik, NIEHS "Research Strategies for Exploring the Landscape of Environmental Health"
4:00 pm - 5:00 pm, Toxicology Building Auditorium

Welcome New Members
Full Membership
Scott Belcher, Research Professor, Dept. of Biological Sciences, NCSU

Associate Membership
Madhavi Kakumanu, Postdoctoral Research Scholar, Dept. of Entomlogy and Plant Pathology, NCSU

CHHE and CMI are sponsoring a joint seminar by the Director of the Human Pluripotent Stem Cell Core Facility at UNC. Dr Adriana Beltran will discuss how the Facility's expertise could help your research. April 13th, 3:30-4:30pm, Room 2104, Toxicology Building Auditorium. All are welcome: faculty, postdocs, staff and students! 
Services include:
- generation of iPS cells
- differentiation of iPS and ES cells
- genome editing with TALEN/CRISPR
- gene regulation and chromatin remodeling with ZFP, TALEN and CRISPR technologies

The CHHE Comparative Pathology Core is pleased to provide a lunch seminar on RNAscope Technology (Advanced Cell Diagnostics). RNAscope assay is a proprietary RNA in situ hybridization assay for use in tissues (frozen or paraffin) or cells. Advantages include: single RNA molecule detection at single-cell resolution; dual ISH-IHC  and multiplex assays; quantitative capability; and many others. Please join us for this seminar on April 19th, 12-1 PM, Room 2104, Toxicology Building Auditorium. Lunch will be provided and the seminar will be followed by a Q & A session with an experienced field application scientist who welcomes your questions on technical and experimental details. Please register at the following link 

Associate Membership Available for Post-doctoral fellows: Postdocs and Research Associates with interests in Environmental Health Science can apply for Associate Membership in the Center. Prospective new members may self-nominate or be nominated by a CHHE member. The criteria for Associate Membership in the Center are: 1) Postdoc or Research Associate status at one of the CHHE partners; 2) significant interest in environmental health science; and 3) relevance of the individual’s research program to environmental health science.
Congratulations to Greg Kearney, ECU, for hosting the highly successful Climate Change and Health Symposium: Focus on Eastern NC in March 2017!  The meeting was well-organized, well-attended, dynamic meeting with a broad range of engaged stakeholders.  We look forward to more CHHE events in Eastern North Carolina.


Congratulations to CHHE's new authors: Heather Patisual and Scott Belcher just published a book entitled Endocrine Disruptors, Brain, and Behavior [see CHHE news link], and Rob Dunn just published a new book, Never out of Season.  Happy reading!

New Grant:  Seth Kullman with co-PI Heather Stapleton received an NIEHS R01 entitled "Altering the Balance of Adipogenic and Ostegenic Regulatory Pathways from Early Life Exposure to Halogenated Phenolic Contaminants and Organophosphates" as part of the Duke University superfund program (P42) that was just re-approved.  The focus of the grant is to investigate how brominated and OP-flame retardants alter thyroid hormone receptor  and PPAR gamma cross talk regulating adipogenic and osteogenic programs. They will be working in both human mesenchymal stem cells and with zebrafish.  Congratulations Seth!

CHHE director Rob Smart is a recipient of the Research Leadership Academy and 2016-2017 Alumni Association Outstanding Research Award.  He will be recognized at the 2017 Faculty Awards and Mathews Medal Ceremony to be held on April 26 at the Park Alumni Center.  Congratulations Rob and thanks for all your hard work in making the Center a reality!

Congratulations to Dr. Jun Ninomiya-Tsuji, COS nominee for the University’s Outstanding Global Engagement Award.  Jun will be recognized for her achievements in the globalization of research and training at the Global Engagement Exposition to be held April 18th at Talley Student Union.

COEC Update

The COEC's proposal for a symposia at the International Society of Exposure Science (ISES) was accepted this month. Katy will be presenting with members and community partners from NYU and Emory's COECs on how to effectively involve community partners in exposure science. The COEC was also part of a proposal to NIEHS for funding to conduct community-based participatory research on toxic metal exposure in Durham. 

Interested in having your research take a more community-based approach? Email to find out how! 


PINS: Remember when submitting your grants, be sure to select "Center for Human Health and the Environment" as a center in PINS.

Acknowledgements: Remember to cite our CHHE grant P30ES025128 in publications if CHHE has provided you services, facility core use, seed/pilot project funds etc. NIH tracks this as an important CHHE metric.

CHHE Logo: Please use the CHHE logo in your presentations. You can find it on the

CHHE Resources and Facilities Page for NIH Grants is now available on the CHHE


Rick Woychik, NIEHS
"Research Strategies for Exploring the Landscape of Environmental Health"
April 25, 2017 Toxicology Building Auditorium 4:00 pm - 5:00 pm

CHHE Calendar of events

CHHE Member Resources 
CHHE offers a host of resources for Center members: seed money for use in Facility Cores, Facility Cores for Pathology, Proteomics, Genomics, and Metabolomics, bioinformatic support, career development opportunities, travel funds, and more.  Check out the website for more details.  And, remember, if you take advantage of these resources be sure to cite the Center (P30ES025128) in the acknowledgments of papers.

Research Money for CHHE members: CHHE Seed Funds
CHHE is providing up to $5000/year to each CHHE member to defray the cost associated with using the Comparative Pathology Core (immunohistochemical staining , tissue embedding and processing, etc.) or the Systems Technologies Core, including the Genomics (RNAseq etc), Proteomics (targeted and discovery proteomics), and Metabolomics sections (analysis of endorgenous and exogenous compounds; metals, xenobiotics etc) for environmental health science related projects. CHHE will also consider providing funds to support EHS research associated with the Integrative Health Sciences Facility and Community Outreach and Engagement Cores. For more details, click on 

CHHE 2016 Travel/Workshop Award Announcement - - Rolling deadline
One of CHHE's missions is to support career development of new and early stage investigators. As part of the effort, CHHE will provide awards (up to $1,000) to help defray the cost of travel to scientific meetings or small symposia relevant to environmental health science or a workshop that will provide new skills. Travel/Workshop awards will be reviewed and prioritized by members of the 
Career Development Core. Your request should be succinct (less than 250 words) and document the importance of attending the requested meeting/workshop. Please aldo include the entire budget for travel/registration, etc. Please send your proposals to Jackie Broughton.

**See the for more information**

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Center for Human Health and the Environment · NC State University · Campus Box 7633 · Raleigh, NC 27607 · USA

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