Vol. 2 No. 5 August 2016
2016 CHHE Pilot Project Awards

Congratulations to recipients of 2016 CHHE Pilot Project Awards!  CHHE awarded nine Pilot Projects in the amount of $25,000 each to investigators across several colleges at NCSU, as well as investigators at ECU Brody School of Medicine and NC Central University. These year long projects are intended to foster collaboration among CHHE members and generate preliminary data for larger grant applications to NIEHS. 

Benzoic acid in beverages: Establishing a link between urinary metabolites, metabolic dysregulation and weight loss failure
David N. Collier (PI), ECU
Carolyn J. Mattingly (Co-I), COS
Susan Sumner (Consultant), RTI

Behavior and specific gene alterations after prenatal exposure to arsenic
Zuzana Drobna (PI), COS

Mechanisms of nanoparticle endocytosis and the subsequent effects on extracellular matrix deposition and epithelial cell adhesion
Jodie M. Fleming (PI), NCCU
Michael Bereman (Co-I), COS
John J. Bang (Co-I), NCCU
James C. Bonner (Co-I), COS

Establishing a targeted genomic map of quantified transcriptional and epigenetic modifications associated with AhR mediated repression of mesenchymal stem cell differentiation 
Seth W. Kullman (PI), COS
Michael Cowley (Co-I), COS
Yoshiaki Tsuji (Co-I), COS

Epigenetic modulation and hypothalamic leptin resistance in toxic metal exposures
Jun Ninomiya-Tsuji (PI), COS
Mike Cowley (Collaborator), COS

Arsenic Treatment of contaminated water using surface-functionalized fabrics
Matthew Polizzotto (PI), CALS
Stephen Michielsen (Co-I), COT
David Buchwalter (Co-I), COS
Dean Hesterberg (Co-I), CALS
Francois Birgand (Co-I), COE/CALS

The role of upstream stimulatory factor in tumor suppression
Michael Sikes (PI), COS

Characterization of pulmonary lymphocytes involved in exacerbation of environmental lung disease by microbial antigen
Mary Jane Thomassen (PI), ECU
Christopher Wingard (Co-I), ECU
Robert Barrington (Co-I), USA

Telomeric cohesin complex and DNA damage induced telomere instability 
Hong Wang (PI), COS

COEC Update

Community Outreach and Engagement Core
The COEC has spent much of July working on its Community Mini Grant Program. We sent out our official call for proposals on July 1, and since then have been receiving enthusiastic emails and phone calls from interested community groups across the state on a daily basis. In order to enhance people's grant-writing capacity, the COEC and Chris McGahan of the Career Development Core hosted a grant-writing workshop on July 25 with more than 20 participants in person and online. Grant applications will be due August 15, and we can't wait to see what they look like! For more information on the Mini Grant Program or the Workshop, click here.


PINS: Remember when submitting your grants, be sure to select "Center for Human Health and the Environment" as a center in PINS.

Acknowledgements: Remember to cite our CHHE grant P30ES025128 in publications if CHHE has provided you services, facility core use, seed/pilot project funds etc. NIH tracks this as an important CHHE metric.

CHHE Logo: Please use the CHHE logo in your presentations. You can find it on the

CHHE Resources and Facilities Page for NIH Grants is now available on the CHHE


Seminars: Send Jackie seminar announcements/events etc. for the CHHE calendar.

CHHE Member Resources 
The CHHE has cores for members to use to enhance their research. Seed money is available to members to spend in the cores.  These cores are:

The Comparative Pathology Core  provides pathology training, laser capture microdissection and pathology assessment of a diverse range of model organisms as well consultation
and opportunities for collaboration.

The Integrative Health Science Facility Core can help you translate your findings from animal/cell models to humans or vice versa.  This core can help you obtain human tissues/specimens, help with conduct of human studies (questionnaire development, IRB assistance), use of the comparative toxicogenomic database (CTD, either with specialized training or data curation, access to clinical populations at ECU, and much more.

The Systems Technologies Core provides genomic, metabolomics and proteomic analysis as well as consultation and opportunities for collaboration.

Dedicated Bioinformatic support is available for CHHE members.

Career Development Core provides grant writing help to early stage investigators and those new to environmental health sciences research. This core also provides funding for early stage investigators to attend a scientific meeting/workshop. 

Community Outreach and Engagement Core (COEC) extends the reach of our research to communities in NC and beyond. The COEC can help you translate your research findings for the general public.

Research Money for CHHE members: CHHE Seed Funds
CHE is providing up to $3000/year to each CHHE member to defray the cost associated with using the Comparative Pathology Core (immunohistochemical staining , tissue embedding and processing, etc.) or the Systems Technologies Core, including the Genomics (RNAseq etc), Proteomics (targeted and discovery proteomics), and Metabolomics sections (analysis of endorgenous and exogenous compounds; metals, xenobiotics etc) for environmental health science related projects. CHHE will also consider providing funds to support EHS research associated with the Integrative Health Sciences Facility and Community Outreach and Engagement Cores. For more details, click on 

SEED Projects with the NIH Common Fund Metabolomics Core at RTI
One of the CHHE partners is the Metabolomics Core at RTI. This Core serves as the NIH Common Fund Eastern Regional Comprehensive Metabolomics Resource Core (ERCMRC), and as a NIEHS Children’s Exposure Analysis Resource (CHEAR) Hub. Researchers at RTI are interested in collaborating with CHHE members to conduct pilot studies to measure environmentally relevant compounds, and perform metabolomics analysis of cells, tissue, and biological fluids.
Susan Sumner to discuss potential projects that can be funded through the  ERCMRC at RTI.  Selected Seed projects would be performed for studies involving up to 50 samples, with preliminary data used for subsequent proposal submissions.

CHHE 2016 Travel/Workshop Award Announcement - - Rolling deadline
One of CHHE's missions is to support career development of new and early stage investigators. As part of the effort, CHHE will provide awards (up to $1,000) to help defray the cost of travel to scientific meetings or small symposia relevant to environmental health science or a workshop that will provide new skills. Travel/Workshop awards will be reviewed and prioritized by members of the 
Career Development Core. Your request should be succinct (less than 250 words) and document the importance of attending the requested meeting/workshop. Please aldo include the entire budget for travel/registration, etc. Please send your proposals to Jackie Broughton.

**See the for more information**

Recent CHHE Publications

Bayesian multinomial probit modeling of daily windows of susceptibility for maternal PM2.5 exposure and congenital heart defects
By: Warren, Joshua L.; Stingone, Jeanette A.; Herring, Amy H.; Luben, TJ; Fuentes, M; et al.
Group Author(s): Natl Birth Defects Prevention
Statistics in Medicine Volume: 35 Issue: 16 Pages: 2786-2801 Published: JUL 20 2016

Artificial selection on chill-coma recovery time in Drosophila melanogaster: Direct and correlated responses to selection
By: Gerken, Alison R.; Mackay, Trudy F. C.; Morgan, Theodore J.
Journal of Thermal Biology Volume: 59 Pages: 77-85 Published: JUL 2016
Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy
By: Friedenberg, Steven G.; Chdid, Lhoucine; Keene, Bruce; Sherry, B; Motsinger-Reif, A; et al.
American Journal of Veterinary Research Volume: 77 Issue: 7 Pages: 693-699 Published: JUL 2016
Diphenhydramine exposure in dogs: 621 cases (2008-2013)
By: Worth, Alisha C.; Wismer, Tina A.; Dorman, David C.
Javam-Journal of the American Veterinary Medical Association Volume: 249 Issue: 1 Pages: 77-82 Published: JUL 1 2016
Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure
By: Zhang, Guozhu; Marvel, Skylar; Truong, Lisa; Tanguay, RL ; Reif, DM 
Reproductive Toxicology Volume: 62 Pages: 92-99 Published: JUL 2016

Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials
By: Clippinger, Amy J.; Ahluwalia, Arti; Allen, David; Bonner, JC; et al.
Archives of Toxicology Volume: 90 Issue: 7 Pages: 1769-1783 Published: JUL 2016

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies
By: Irvin, Marguerite R.; Rotroff, Daniel M.; Aslibekyan, Stella;  Zhi, DG ; Hidalgo, B ; Motsinger-Reif, A ; et al.
Pharmacogenetics and Genomics Volume: 26 Issue: 7 Pages: 324-333 Published: JUL 2016

Insecticide resistance and nutrition interactively shape life-history parameters in German cockroaches
By: Jensen, Kim; Ko, Alexander E.; Schal, Coby; et al.
Scientific Reports Volume: 6 Article Number: 28731 Published: JUN 27 2016

Bioaccumulation Dynamics of Arsenate at the Base of Aquatic Food Webs
By: Lopez, Adeline R.; Hesterberg, Dean R.; Funk, David H.; Buchwalter, DB 
Environmental Science & Technology Volume: 50 Issue: 12 Pages: 6556-6564 Published: JUN 21 2016

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans
By: Rotroff, Daniel M.; Oki, Noffisat O.; Liang, Xiaomin;  Yee, SW; Stocker, SL; Corum, DG ; Meisner, M ; Fiehn, O ; Motsinger-Reif, AA; et al.
Frontiers in Pharmacology Volume: 7 Article Number: 135 Published: JUN 14 2016

Maternal Early Pregnancy Serum Metabolomics Profile and Abnormal Vaginal Bleeding as Predictors of Placental Abruption: A Prospective Study
By: Gelaye, Bizu; Sumner, Susan J.; McRitchie, Susan; et al.
Plos One Volume: 11 Issue: 6 Article Number: e0156755 Published: JUN 14 2016

Honey Bee (Apis mellifera) Queen Reproductive Potential Affects Queen Mandibular Gland Pheromone Composition and Worker Retinue Response
By: Rangel, Juliana; Boroczky, Katalin; Schal, Coby; et al.
Plos One Volume: 11 Issue: 6 Article Number: e0156027 Published: JUN 9 2016

Atomic layer deposition coating of carbon nanotubes with zinc oxide causes acute phase immune responses in human monocytes in vitro and in mice after pulmonary exposure
By: Dandley, Erinn C.; Taylor, Alexia J.; Duke, Katherine S.; Ihrie, MD; Shipkowski, KA; Parsons, GN; Bonner, JC
Particle and Fibre Toxicology Volume: 13 Article Number: 29 Published: JUN 8 2016

Genome-Wide Association Study in Immunocompetent Patients with Delayed Hypersensitivity to Sulfonamide Antimicrobials
By: Reinhart, Jennifer M.; Motsinger-Reif, Alison; Dickey, Allison; et al.
Plos One Volume: 11 Issue: 6 Article Number: e0156000 Published: JUN 7 2016

Microfluidics meets metabolomics to reveal the impact of Campylobacter jejuni infection on biochemical pathways
By: Mortensen, Ninell P.; Mercier, Kelly A.; McRitchie, Susan; Cavallo, TB; Pathmasiri, W; Stewart, D; Sumner, SJ
Biomedical Microdevices Volume: 18 Issue: 3 Article Number: 51 Published: JUN 2016

Habitat use by adult red wolves, Canis rufus, in an agricultural landscape, North Carolina, USA
By: Karlin, Melissa; Vaclavik, Tomas; Chadwick, John; Meentemeyer, R
Mammal Study Volume: 41 Issue: 2 Pages: 87-95 Published: JUN 2016

Listeria monocytogenes septicemia in an immunocompromised dog
By: Pritchard, Jessica C.; Jacob, Megan E.; Ward, Todd J.; Parsons, CT ; Kathariou, S; et al.
Veterinary Clinical Pathology Volume: 45 Issue: 2 Pages: 254-259 Published: JUN 2016

Testing and estimation in marker-set association study using semiparametric quantile regression kernel machine
By: Kong, Dehan; Maity, Arnab; Hsu, Fang-Chi; Tzeng, JY
Biometrics Volume: 72 Issue: 2 Pages: 364-371 Published: JUN 2016

Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis
By: Lange, Clemens; Mowat, Freya; Sayed, Haroon; et al.
Experimental Eye Research Volume: 147 Pages: 148-155 Published: JUN 2016

The confounding complexity of innate immune receptors within and between teleost species
By: Wcisel, Dustin J.; Yoder, Jeffrey A.
Fish & Shellfish Immunology Volume: 53 Special Issue: SI Pages: 24-34 Published: JUN 2016

Analysis of maternal polymorphisms in arsenic (+3 oxidation state)-methyltransferase AS3MT and fetal sex in relation to arsenic metabolism and infant birth outcomes: Implications for risk analysis
By: Drobna, Zuzana; Martin, Elizabeth; Kim, Kyung Su; et al.
Reproductive Toxicology Volume: 61 Pages: 28-38 Published: JUN 2016

The effect of high dose oral manganese exposure on copper, iron and zinc levels in rats
By: Mercadante, Courtney J.; Herrera, Carolina; Pettiglio, Michael A.; Foster, ML ; Johnson, LC ; Dorman, DC
 Volume: 29 Issue: 3 Pages: 417-422 Published: JUN 2016

alpha-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance
By: Cobb, Jeff; Eckhart, Andrea; Motsinger-Reif, Alison; et al.
Diabetes Care Volume: 39 Issue: 6 Pages: 988-995 Published: JUN 2016

Assessment of sex specific endocrine disrupting effects in the prenatal and pre-pubertal rodent brain
By: Rebuli, Meghan E.; Patisaul, Heather B.
Conference: 8th International Meeting on Steroids and Nervous System Location: Orbassano, ITALY Date: 2015

Journal of Steroid Biochemistry and Molecular Biology Volume: 160 Special Issue: SI Pages: 148-159 Published: JUN 2016

High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes
By: Reif, David M.; Truong, Lisa; Mandrell, David; et al.
Archives of Toxicology Volume: 90 Issue: 6 Pages: 1459-1470 Published: JUN 2016

Association between Prepregnancy Body Mass Index and Gestational Weight Gain with Size, Tempo, and Velocity of Infant Growth: Analysis of the Newborn Epigenetic Study Cohort
By: Fuemmeler, Bernard F.; Wang, Lin; Iversen, Edwin S.; Maguire, R ; Murphy, SK; Hoyo, C
Childhood Obesity Volume: 12 Issue: 3 Special Issue: SI Pages: 210-218 Published: JUN 2016

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons (vol 48, pg 427, 2016)
By: Braasch, Ingo; Gehrke, Andrew R.; Smith, Jeramiah J.; Yoder, JA; et al.
Nature Genetics Volume: 48 Issue: 6 Pages: 700-700 Published: JUN 2016

Carboplatin/taxane-induced gastrointestinal toxicity: a pharmacogenomics study on the SCOTROC1 trial
By: He, Y. J.; Winham, S. J.; Hoskins, J. M.; Glass, S; Paul, J; Brown, R; Motsinger-Reif, A; et al.
Group Author(s): Scottish Gynaecological Canc

Pharmacogenomics Journal Volume: 16 Issue: 3 Pages: 243-248 Published: JUN 2016

Biological and behavioral factors modify urinary arsenic metabolic profiles in a US population
By: Hudgens, Edward E.; Drobna, Zuzana; He, Bin; et al.
Environmental Health Volume: 15 Article Number: 62 Published: MAY 26 2016

Modeling when, where, and how to manage a forest epidemic, motivated by sudden oak death in California
By: Cunniffe, Nik J.; Cobb, Richard C.; Meentemeyer, Ross K.; et al.
Proceedings of the National Academy of Sciences of the United States of America Volume: 113 Issue: 20 Pages: 5640-5645 Published: MAY 17 2016

Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database
By: Davis, Allan Peter; Wiegers, Thomas C.; King, Benjamin L.; Wiegers, J; Grondin, CJ; Sciaky, D ; Johnson, RJ; Mattingly, CJ
Plos One Volume: 11 Issue: 5 Article Number: e0155530 Published: MAY 12 2016

BioCreative V CDR task corpus: a resource for chemical disease relation extraction
By: Li, Jiao; Sun, Yueping; Johnson, Robin J.; Sciaky, D; Wei, CH; Leaman, R; Davis, AP; Mattingly, CJ; et al.

ToxEvaluator: an integrated computational platform to aid the interpretation of toxicology study-related findings
By: Pelletier, D.; Wiegers, T. C.; Enayetallah, A.; Kibbey, C; Gosink, M; Koza-Taylor, P; Mattingly, CJ; et al.
Database - The Journal of Biological Databases and Curation Article Number: baw062 Published: MAY 9 2016

Obesity-related DNA methylation at imprinted genes in human sperm: Results from the TIEGER study
By: Soubry, Adelheid; Guo, Lisa; Huang, Zhiqing; Hoyo, C; et al.
Clinical Epigenetics Volume: 8 Article Number: 51 Published: MAY 6 2016

Effect of Indaziflam Applications on 'Tifway 419' Bermudagrass Growth
By: Jeffries, Matthew D.; Gannon, Travis W.; Ou, Ling
Agronomy Journal Volume: 108 Issue: 3 Pages: 950-956 Published: MAY-JUN 2016

Use of Dieselized Farm Equipment and Incident Lung Cancer: Findings from the Agricultural Health Study Cohort
By: Tual, Severine; Silverman, Debra T.; Koutros, Stella;  Blair, A ; Sandler, DP; Lebailly, P; Andreotti, G; Hoppin, JA; Freeman, LEB
Environmental Health Perspectives Volume: 124 Issue: 5 Pages: 611-618 Published: MAY 2016

Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood
By: Li, Yue; Xie, Changchun; Murphy, Susan K.; Skaar, D; Nye, M; Vidal, AC; Cecil, KM; Dietrich, KN; Puga, A; Jirtle, RL; et al.
Environmental Health Perspectives Volume: 124 Issue: 5 Pages: 666-673 Published: MAY 2016

Genetic Background, Maternal Age, and Interaction Effects Mediate Rates of Crossing Over in Drosophila melanogaster Females
By: Hunter, Chad M.; Robinson, Matthew C.; Aylor, David L.; et al.
G3-Genes Genomes Genetics Volume: 6 Issue: 5 Pages: 1409-1416 Published: MAY 2016

TransOmic analysis of forebrain sections in Sp2 conditional knockout embryonic mice using IR-MALDESI imaging of lipids and LC-MS/MS label-free proteomics
By: Loziuk, Philip; Meier, Florian; Johnson, Caroline;  Ghashghaei, HT; Muddiman, DC
Analytical and Bioanalytical Chemistry Volume: 408 Issue: 13 Pages: 3453-3474 Published: MAY 2016

Calbindin Knockout Alters Sex-Specific Regulation of Behavior and Gene Expression in Amygdala and Prefrontal Cortex
By: Harris, Erin P.; Abel, Jean M.; Tejada, Lucia D.; Rissman, EF
Endocrinology Volume: 157 Issue: 5 Pages: 1967-1979 Published: MAY 2016

Observed and self-reported pesticide protective behaviors of Latino migrant and seasonal farmworkers
By: Walton, AnnMarie Lee; LePrevost, Catherine; Wong, Bob; et al.
Environmental Research Volume: 147 Pages: 275-283 Published: MAY 2016

Across-Platform Imputation of DNA Methylation Levels Incorporating Nonlocal Information Using Penalized Functional Regression
By: Zhang, Guosheng; Huang, Kuan-Chieh; Xu, Zheng; Tzeng, JY; et al.
Genetic Epidemiology   Volume: 40   Issue: 4   Pages: 333-340   Published: MAY 2016

TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus
By: Sai, Kazuhito; Morioka, Sho; Takaesu, Giichi; Muthusamy, N; Ghashghaei, HT; Hanafusa, H; Matsumoto, K; Ninomiya-Tsuji, J; et al.
Journal of Cell Sciences Volume: 129 Issue: 9 Pages: 1855-1865 Published: MAY 2016

Capacity of Listeria monocytogenes Strains from the 2011 Cantaloupe Outbreak To Adhere, Survive, and Grow on Cantaloupe
By: Martinez, Mira Rakic; Osborne, Jason; Jayeola, Victor Oladimeji;  Katic, V; Kathariou, S
Journal of Food Protection Volume: 79 Issue: 5 Pages: 757-763 Published: MAY 2016

Natural variability in Drosophila larval and pupal NaCl tolerance
By: Riedl, Craig A. L.; Oster, Sara; Busto, Macarena; Mackay, TFC; et al.
Journal of Insect Physiology Volume: 88 Pages: 15-23 Published: MAY

Can't take the heat: Temperature-enhanced toxicity in the mayfly Isonychia bicolor exposed to the neonicotinoid insecticide imidacloprid
By: Camp AA,; Buchwalter DB.
Aquat Toxicol. 2016 Jul 19;178:49-57. doi: 10.1016/j.aquatox.2016.07.011. [Epub ahead of print]

Chemical controls on abiotic and biotic release of geogenic arsenic from Pleistocene aquifer sediments to groundwater
By: Gillispie EC,; Andujar E,; Polizzotto ML.
Environ Sci Process Impacts. 2016 Jul 27. [Epub ahead of print]

Relative Contributions of Agricultural Drift, Para-Occupational, and Residential Use Exposure Pathways to House Dust Pesticide Concentrations: Meta-Regression of Published Data
By: Deziel NC.; Beane Freeman LE; Graubard BI; Jones RR; Hoppin JA; Thomas K.; Hines CJ; Blair A.; Sandler DP; Chen H.; Lubin JH; Andreotti G.; Alavanja MC; Friesen MC.
Environ Health Perspect. 2016 Jul 26. [Epub ahead of print] Review.

Still Separate, Still Unequal: Social Determinants of Playground Safety and Proximity Disparities in St. Louis
By: Arroyo-Johnson C.; Woodward K.; Milam L.; Ackermann N.; Komaie G.; Goodman MS; Hipp JA.
J Urban Health. 2016 Jul 8. [Epub ahead of print]

Sharing the Roles: An Assessment of Japanese Medaka Estrogen Receptors in Vitellogenin Induction
By: Lee Pow CS; Yost EE; Aday DD; Kullman SW.
Environ Sci Technol. 2016 Jul 26. [Epub ahead of print]

Occupational Exposure to Pesticides and the Incidence of Lung Cancer in the Agricultural Health Study
By: Bonner MR; Beane Freeman LE; Hoppin JA; Koutros S.; Sandler DP; Lynch CF; Hines CJ; Thomas K.; Blair A.; Alavanja MC.
Environ Health Perspect. 2016 Jul 6. [Epub ahead of print]

Pesticides Are Associated with Allergic and Non-Allergic Wheeze among Male Farmers
By: Hoppin JA; Umbach DM; Long S.; London SJ; Henneberger PK; Blair A.; Alavanja M.; Beane Freeman LE; Sandler DP.
Environ Health Perspect. 2016 Jul 6. [Epub ahead of print]

Biofilm Formation by Environmental Isolates of Salmonella and Their Sensitivity to Natural Antimicrobials
By: Keelara S.; Thakur S.; Patel J.
Foodborne Pathog Dis. 2016 Jun 29. [Epub ahead of print]

Mucous membrane pemphigoid in dogs: a retrospective study of 16 new cases
By: Tham HL; Olivry T.; Linder KE; Bizikova P
Vet Dermatol. 2016 Jun 28. doi: 10.1111/vde.12344. [Epub ahead of print]

Angiopellosis as an Alternative Mechanism of Cell Extravasation
By: Allen TA; Gracieux D.; Talib M.; Tokarz DA; Hensley MT; Cores J.; Vandergriff A.; Tang J.; de Andrade JB; Dinh PU; Yoder JA; Cheng K.
Stem Cells. 2016 Jun 28. doi: 10.1002/stem.2451. [Epub ahead of print]

Early Activation of Th2/Th22 Inflammatory and Pruritogenic Pathways in Acute Canine Atopic Dermatitis Skin Lesions
By: Olivry T.; Mayhew D.; Paps JS; Linder KE; Peredo C.; Rajpal D.; Hofland H.; Cote-Sierra J.
J Invest Dermatol. 2016 Jun 21. pii: S0022-202X(16)31360-4. doi: 10.1016/j.jid.2016.05.117. [Epub ahead of print]

Retrospective: Acute Toxicity of Priority Pollutants
By: LeBlanc GA.
Bull Environ Contam Toxicol. 2016 Jun 22. [Epub ahead of print] No abstract available.

Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development
By: Macaulay LJ.; Chernick M.; Chen A.; Hinton DE; Bailey JM; Kullman SW; Levin ED; Stapleton HM.
Environ Toxicol Chem. 2016 Jun 22. doi: 10.1002/etc.3535. [Epub ahead of print]

Advancing toxicology research using in vivo high throughput toxicology with small fish models
By: Planchart AMattingly CJ; Allen D.; Ceger P.; Casey W.; Hinton D.; Kanungo J.; Kullman SW; Tal T.; Bondesson M.; Burgess SM.; Sullivan C.; Kim C.; Behl M.; Padilla S.; Reif DM; Tanguay RL; Hamm J.
ALTEX. 2016 Jun 21. doi: 10.14573/altex.1601281. [Epub ahead of print]

Neonatal masculinization blocks increased excitatory synaptic input in female rat nucleus accumbens core
By: Cao J, Dorris DM, Meitzen J.
Endocrinology. 2016 Jun 10:en20161160. [Epub ahead of print]

No Evidence of Reciprocal Associations between Daily Sleep and Physical Activity
By: Mitchell JA, Godbole S, Moran K, Murray K, James P, Laden F, Hipp JA, Kerr J, Glanz K.
Med Sci Sports Exerc. 2016 Jun 9. [Epub ahead of print]

Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures
By: Parks CG, Hoppin JA, DeRoos AJ, Costenbader KH, Alavanja MC, Sandler DP.
Environ Health Perspect. 2016 Jun 10. [Epub ahead of print]

Infective endocarditis in 13 cats.
By: Palerme JS, Jones AE, Ward JL, Balakrishnan N, Linder KE, Breitschwerdt EB, Keene BW.
J Vet Cardiol. 2016 Jun 6. pii: S1760-2734(16)30024-8. doi: 10.1016/j.jvc.2016.04.003. [Epub ahead of print]

Novel plasmid conferring kanamycin and tetracycline resistance in the turkey-derived Campylobacter jejuni strain 11601MD
By:" Crespo MD, Altermann E, Olson J, Miller WG, Chandrashekhar K, Kathariou S.
Plasmid. 2016 Jul;86:32-7. doi: 10.1016/j.plasmid.2016.06.001. Epub 2016 Jun 4.

TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1
By: Hashimoto K, Simmons AN, Kajino-Sakamoto R, Tsuji Y, Ninomiya-Tsuji J.
Antioxid Redox Signal. 2016 Jun 30. [Epub ahead of print]

The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures
By: Feinstein DL, Akpa BS, Ayee MA, Boullerne AI, Braun D, Brodsky SV, Gidalevitz D, Hauck Z, Kalinin S, Kowal K, Kuzmenko I, Lis K, Marangoni N, Martynowycz MW, Rubinstein I, van Breemen R, Ware K, Weinberg G.
Ann N Y Acad Sci. 2016 Jun;1374(1):111-22. doi: 10.1111/nyas.13085. Epub 2016 May 31.

Webcams, Crowdsourcing, and Enhanced Crosswalks: Developing a Novel Method to Analyze Active Transportation
By: Hipp JA, Manteiga A, Burgess A, Stylianou A, Pless R.
Front Public Health. 2016 May 19;4:97. doi: 10.3389/fpubh.2016.00097. eCollection 2016.

Autosomal recessive congenital ichthyosis due to PNPLA1 mutation in a golden retriever-poodle cross-bred dog and the effect of topical therapy
By: Tamamoto-Mochizuki C, Banovic F, Bizikova P, Laprais A, Linder KE, Olivry T.
Vet Dermatol. 2016 Aug;27(4):306-e75. doi: 10.1111/vde.12323. Epub 2016 May 30.

Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories in Drosophila melanogaster
By: Edwards SM, Sørensen IF, Sarup P, Mackay TF, Sørensen P.
Genetics. 2016 May 27. pii: genetics.116.187161. [Epub ahead of print]

TAK1 regulates hepatic lipid homeostasis through SREBP
By: Morioka S, Sai K, Omori E, Ikeda Y, Matsumoto K, Ninomiya-Tsuji J.
Oncogene. 2016 Jul 21;35(29):3829-38. doi: 10.1038/onc.2015.453. Epub 2016 Mar 14.

Spontaneous mutations and the origin and maintenance of quantitative genetic variation
By: Huang W, Lyman RF, Lyman RA, Carbone MA, Harbison ST, Magwire MM, Mackay TF.
Elife. 2016 May 23;5. pii: e14625. doi: 10.7554/eLife.14625.

Initial characterization of stiff skin-like syndrome in West Highland white terriers
By: Doelle M, Linder KE, Boche J, Jagannathan V, Leeb T, Linek M.
Vet Dermatol. 2016 Jun;27(3):210-e53. doi: 10.1111/vde.12316.

Lamellipodia are crucial for haptotactic sensing and response
By: King SJ, Asokan SB, Haynes EM, Zimmerman SP, Rotty JD, Alb JG Jr, Tagliatela A, Blake DR, Lebedeva IP, Marston D, Johnson HE, Parsons M, Sharpless NE, Kuhlman B, Haugh JM, Bear JE.
J Cell Sci. 2016 Jun 15;129(12):2329-42. doi: 10.1242/jcs.184507. Epub 2016 May 12

Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database
By: Grondin CJ, Davis AP, Wiegers TC, King BL, Wiegers JA, Reif DM, Hoppin JA, Mattingly CJ.
Environ Health Perspect. 2016 May 12. [Epub ahead of print]

Improving the analytical performance and versatility of paper spray mass spectrometry via paper microfluidics
By: Murray I, Walker G, Bereman MS.
Analyst. 2016 Jun 20;141(13):4065-73. doi: 10.1039/c6an00649c.

ParkIndex: Development of a standardized metric of park access for research and planning
By: Kaczynski AT, Schipperijn J, Hipp JA, Besenyi GM, Wilhelm Stanis SA, Hughey SM, Wilcox S.
Prev Med. 2016 Jun;87:110-4. doi: 10.1016/j.ypmed.2016.02.012. Epub 2016 Feb 8.


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