Vol. 2 No.3/4 June/July 2016
Sarah A. Robertson, University of Adelaide
"Paternal Factors Impacting Periconception Origins of Health"

Professor Sarah Robertson is Director of the University of Adelaide’s Robinson Research Institute and Head of the Reproductive Immunology research group. She is an internationally-renowned reproductive biologist whose innovative research in reproductive immunology has formed the basis for a new understanding of the origins of health at conception.
July 11, 2016 Toxicology Auditorium 10 am 

CHHE had a busy May. On May 3, CHHE had the Comparative Pathology Core information session.  The session was well attended and identified additional core resources at UNC available to NC State faculty.
On May 11, Ingenuity Pathway Analysis software training was attended by more than 60 people.  This software will help CHHE members, NC State faculty and their laboratories interpret their biological data faster.
On May 20, CHHE held its first External Advisory Committee meeting with John Essigmann from MIT, Margaret Karagas from Dartmouth, and Kathleen Gray from UNC.  Also attending were Claudia Thompson, the CHHE program officer at NIEHS, and Randy Woodson, NC State Chancellor.  During this day long meeting, we reviewed the activities of the center in its first year and solicited suggestions for moving forward.  The External Advisory Committee was very impressed with what we've been doing, and some of them even took our ideas home with them to implement at their own centers!

Congratulations to John Meitzen for his first R01 funded by National Institute of Mental Health!  "Elucidating the mechanisms by which estradiol regulates female striatal neuron excitability".  

David Dorman was named a National Associate for the National Research Council!

Congratulations to Robert Anholt was awarded the Alexander Quarles Holladay Medal for Excellence.

Coby Schal received the College of Agriculture and Life Sciences Outstanding Adviser Award!

Jane Hoppin and David Reif received a UGPN International Collaboration to work with researchers at the University of Woolongong in Australia.  Drs. Thomas Astell-Burt and Xiaoqi Feng will come in September to tell CHHE more about their research and collaboration opportunities.

David Reif presented the keynote on applied data science for the basic sciences at the NIEHS Division of Extramural Research and Training (DERT) Data Science Retreat.

David Reif was an invited expert at the U.S. EPA "Expert Workshop on Aggregate Exposure Pathway: A Conceptual Framework to Advance Exposure Science Research and Complete the Source-to-Outcome Continuum for Risk Assessment".

Gina Hilton, graduate student in Michael Bereman's laboratory received Poster Awards at both the NC Society of Toxicology Meeting and the Nanotoxicology Congress for her work ""Identification of Biomarkers for Nano-safety Assessment through Proteomic Analysis of Multi-Walled Carbon Nanotubes Functionalized by Atomic Layer Deposition Coating"

Katie Duke, doctoral student in Jamie Bonner's laboratory received a travel award to the Nanotoxiology Congress for her work "Susceptibility of STAT1-deficient Mice to Pulmonary Fibrosis after Exposure to Tangled vs. Rigid Multi-walled Carbon Nanotubes"

Schal Lab:
Alex Ko successfully defended his PhD dissertation on nutritional ecology and insecticide resistance in the German cockroach. Jamora Hamilton was awarded a National Science Foundation Graduate Research Fellowship Program (GRFP) to investigate the role of gut microbes in aggregation behavior in cockroaches. The award includes a stipend ($34,000/year for 3 years) and an institutional Cost of Education Allowance ($12,000/year), as well as access to various professional development and internship program opportunities offered through the GRFP. Angela Sierras was awarded a $1,500 Graduate Student Scholarship from the North Carolina Pest Management Association. Angela Sierras and Michael Fisher was each awarded a $2,000 scholarship by Pi Chi Omega, the national fraternity of pest management professionals formed in 1950. Zach DeVries (a Ph.D. student) was awarded a $2,000 Foundation for Toxicology and Agromedicine Supplementary Scholarship. Zach also won a $3,000 Pi Chi Omega John V. Osmun Memorial Scholarship and the 2016 National Conference on Urban Entomology Ph.D. Scholarship ($1,500) to present his research at the plenary session in Albuquerque NM in May, and first prize in the student competition of the Southeastern Branch meeting of the Entomological Society of America. Ayako Wada-Katsumata (Senior Researcher) was selected to participate in the Junior Scientist Workshop on Genetic and Neurobiological Basis for Evolution of Behavior at the Janelia Research Campus of the Howard Hughes Medical Institute. Ayako also presented a paper and a poster.
***Send your Kudos to Jane Hoppin every month***
CHHE Pathology Core Update

Keith Linder, Director of the CHHE Comparative Pathology Core hosted an informational meeting for CHHE members and their laboratories to learn about resources available to CHHE members through the Pathology Core as well as resources available at UNC to expand their pathology and analysis capabilities.  David Darr, assistant director for shared resources from UNC’s Lineberger Cancer Center  and Stephanie Montgomery, leader of the animal histopathology core at UNC attended to provide information on resources at UNC. The Comparative Pathology Core provides diverse expertise in a wide variety of animal models and are happy to consult with you throughout your project.  All NC State faculty can use the cores at UNC for UNC rates.  A link to these cores is available above and on the CHHE website

COEC Update

Community Outreach and Engagement Core

In May, the COEC wrapped up work on a new educational website about North Carolina's fish consumption advisories. The site provides information on pollutants, health effects, healthy alternatives, and an interactive map to help you identify what advisories are in effect near you. Check it out here!

The COEC, along with colleagues from UNC-CH and RTI, have been working with community partners in Durham on proposals to continue work related to toxic metals exposure and healthy homes. The group will be collaborating on an NIEHS "Research to Action" grant application over the summer.

After 22 years at NC State, our COEC Associate Director Julia Storm is retiring at the end of June. Julia has been instrumental in the launch of the COEC and will be greatly missed! 

The COEC just launched the mini-grant program for community groups.  Grants are up to $4500 and are due on August 15, 2016.  More details here:


PINS: Remember when submitting your grants, be sure to select "Center for Human Health and the Environment" as a center in PINS.

Acknowledgements: Remember to cite our CHHE grant P30ES025128 in publications if CHHE has provided you services, facility core use, seed/pilot project funds etc. NIH tracks this as an important CHHE metric.

CHHE Logo: Please use the CHHE logo in your presentations. You can find it on the

CHHE Resources and Facilities Page for NIH Grants is now available on the CHHE


Upcoming CHHE Seminars:

Sarah A. Robertson, University of Adelaide
"Paternal Factors Impacting Periconception Origins of Health"
July 11, 2016 Toxicology Auditorium 10 am to 11 am

Seminars: Send Jackie seminar announcements/events etc. for the CHHE calendar.

CHHE Member Resources 
The CHHE has cores for members to use to enhance their research. Seed money is available to members to spend in the cores.  These cores are:

The Comparative Pathology Core  provides pathology training, laser capture microdissection and pathology assessment of a diverse range of model organisms as well consultation
and opportunities for collaboration.

The Integrative Health Science Facility Core can help you translate your findings from animal/cell models to humans or vice versa.  This core can help you obtain human tissues/specimens, help with conduct of human studies (questionnaire development, IRB assistance), use of the comparative toxicogenomic database (CTD, either with specialized training or data curation, access to clinical populations at ECU, and much more.

The Systems Technologies Core provides genomic, metabolomics and proteomic analysis as well as consultation and opportunities for collaboration.

Dedicated Bioinformatic support is available for CHHE members.

Career Development Core provides grant writing help to early stage investigators and those new to environmental health sciences research. This core also provides funding for early stage investigators to attend a scientific meeting/workshop. 

Community Outreach and Engagement Core (COEC) extends the reach of our research to communities in NC and beyond. The COEC can help you translate your research findings for the general public.

Research Money for CHHE members: CHHE Seed Funds
CHE is providing up to $3000/year to each CHHE member to defray the cost associated with using the Comparative Pathology Core (immunohistochemical staining , tissue embedding and processing, etc.) or the Systems Technologies Core, including the Genomics (RNAseq etc), Proteomics (targeted and discovery proteomics), and Metabolomics sections (analysis of endorgenous and exogenous compounds; metals, xenobiotics etc) for environmental health science related projects. CHHE will also consider providing funds to support EHS research associated with the Integrative Health Sciences Facility and Community Outreach and Engagement Cores. For more details, click on 

SEED Projects with the NIH Common Fund Metabolomics Core at RTI
One of the CHHE partners is the Metabolomics Core at RTI. This Core serves as the NIH Common Fund Eastern Regional Comprehensive Metabolomics Resource Core (ERCMRC), and as a NIEHS Children’s Exposure Analysis Resource (CHEAR) Hub. Researchers at RTI are interested in collaborating with CHHE members to conduct pilot studies to measure environmentally relevant compounds, and perform metabolomics analysis of cells, tissue, and biological fluids.
Susan Sumner to discuss potential projects that can be funded through the  ERCMRC at RTI.  Selected Seed projects would be performed for studies involving up to 50 samples, with preliminary data used for subsequent proposal submissions.

CHHE 2016 Travel/Workshop Award Announcement - - Rolling deadline
One of CHHE's missions is to support career development of new and early stage investigators. As part of the effort, CHHE will provide awards (up to $1,000) to help defray the cost of travel to scientific meetings or small symposia relevant to environmental health science or a workshop that will provide new skills. Travel/Workshop awards will be reviewed and prioritized by members of the 
Career Development Core. Your request should be succinct (less than 250 words) and document the importance of attending the requested meeting/workshop. Please aldo include the entire budget for travel/registration, etc. Please send your proposals to Jackie Broughton.

**See the for more information**

Recent CHHE Publications

We will include new publications in the August newsletter! 

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Center for Human Health and the Environment · NC State University · Campus Box 7633 · Raleigh, NC 27607 · USA

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