CRE Network Newsletter #6 - July 2017
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The CRE is a five year NHMRC funded venture between two of the leading hubs in stroke research in Australia - The Florey Institute of Neuroscience and Mental Health in Heidelberg and the Hunter Medical Research Institute in Newcastle.

Stroke Recovery and Rehabilitation Roundtable (SRRR)

The Stroke Recovery and Rehabilitation Roundtable (SRRR) is a group of international collaborators (pictured below) whose goal is to develop consensus-based recommendations to guide stroke recovery research and rehabilitation efforts around the world.
With CRE researchers leading and contributing to this group, The International Journal of Stroke has just published a set of papers arising from the first SRRR meeting in Philadelphia in May 2016.
The papers can all be found here.

The second SRRR meeting, to be held in conjunction with the World Stroke Congress meeting in Montréal in 2018, will focus on international collaboration in stroke recovery research.
Congratulations to all involved for finding consensus and agreeing on a vision for accelerating progress in stroke recovery research.
CRE researchers involved in the SRRR are: Prof Julie Bernhardt, Dr Karen Borschmann, Prof Leeanne Carey, Prof Leonid Churilov, A/Prof Coralie English, Dr Kate Hayward, Dr Liz Lynch and Prof Michael Nilsson.
A podcast with Karen Borschmann and Kate Hayward about the agreed definitions paper can be found here.

Other podcasts with Drs Dale Corbett and Lara Boyd on moving preclinical treatments into the clinical sphere and biomarkers, respectively, can be listened to here and here.

June Newcastle Forum

The open sessions of the June Newcastle Forum which involved the broader CRE network were a great success. 
On the Wednesday evening
Prof Mark Bayley from the University of Ontario, Canada and Dr Peter Thomas, from AAMRI, started the proceedings.
Thursday saw Mark Bayley, give another presentation followed by news from the CRE. Covering diverse topics such as the international landscape, transformational research and practice, collaborative gains and challenges, industry overviews, the Australian Stroke Research Network and 3 minute research snapshots updated everyone about current CRE activities.
The winner of the 3 minute competition was Paul Mackie with runners up Nicola Postol and Gary Crowfoot.
On Friday an Early–Mid Career Implementation Research Workshop with Mark Bayley, Drs Shanthi Ramanathan and Liz Lynch
 gave the attendees lots to think about as they pondered their research and how it could be translated into practice.
If any attendees have comments or suggestions about the forum or what you would like to see at future events please email Jan Chamberlain.
CRE members at the Newcastle forum


22 August: Our work will be presented at the 28th Annual Scientific Meeting of the Stroke Society of Australasia in Queenstown, New Zealand as part of the pre-meeting Rehabilitation Workshop.
11-12 September: Clinical Trials Development and Management Workshop, The Florey, Heidelberg. To register click here.

24 October: Consumer forum.  The Hall, National Australia Bank, 700 Bourke Street (just near Southern Cross Station).
Stay in touch with our activities by checking out our website, Facebook page and Twitter account.

Clinical Trials Development and Management Workshop

You can now register for our 2017 Clinical Trials Development and Management Workshop. It is on Monday 11 and Tuesday 12 September at The Florey in Heidelberg. As last year it will feature expert presenters, facilitated sessions and interactive workshops. Attendees can also attend a networking dinner on the Monday night.
The cost is $600 (incl. GST).
Please register here for the workshop.

News around the CRE streams

AuSCR (Australian Stroke Clinical Registry) recently celebrated 50,000 cases entered. A great achievement by A/Prof Dominique Cadilhac and team.

Prof Linda Worrall from the University of Queensland was interviewed for the World Stroke Organisation's 'Seven minutes in stroke' series. Read about her mentors, collaborations, and the highs and lows of her career in stroke here

The VERSE (Very Early Rehabilitation in Speech) trial at the Tauranga Hospital (New Zealand) was in The Weekend Sun on 30 June. The speech therapy team at Tauranga recruited their first patient in May and they are the second New Zealand Hospital involved in the trial.
A/ Prof Erin Godecke, a CRE Research Affiliate leads the trial which will recruit 246 patients. 
The trial recently received additional funding from the Tavistock Trust for Aphasia.

Virtual reality in stroke research was featured on Channel 7 news. A/Prof Steven Faux spoke about his group's work.

A/Prof Coralie English was interviewed about physical activity and exercise after stroke. Find out about her work in stroke rehabilitation.

Congratulations to Club Melbourne Fellowship winner A/Prof Dominique Cadilhac. The award of $10,000 was for her stroke research at The Florey Institute of Neuroscience and Mental Health.

Stroke Society of Australasia (SSA) meeting

Catch up with many of our researchers at the SSA meeting in Queenstown in August. The Path to Recovery is the theme.
At the pre-meeting Hyper-acute therapies and Rehabilitation workshops A/Prof Erin Godecke,  A/Prof Dominique Cadilhac, Dr Liam Johnson and Prof Chris Bladin are involved.
The draft program can be found online.

Australian Stroke Research Network survey

Dr Karen Borschmann, Australian Stroke Research Network (ASRN), still needs you to complete a survey if you have been involved in stroke research in the last five years. The data being collected from the survey will be presented at the Stroke Society of Australasia meeting in Queenstown in August.

The survey was developed for the Australian Stroke Research Network (ASRN) to explore the nature of existing stroke research networks in Australia, to better facilitate communication and development of stroke research opportunities. Ethics approval was granted by Austin Health Human Research Ethics Committee (Project ID: HREC/16/Austin/529).
Background: The Stroke Foundation and the Stroke Society of Australasia co-funded the establishment of the Australian Stroke Research Network (ASRN) with the following goals:
1. To improve the efficiency and effectiveness of Australian stroke research in reducing the burden of stroke on the Australian community.
2: To encourage interdisciplinary collaboration between stroke researchers, clinicians, and patients.
3: To help develop the research skills, expertise and quality-assured research support capabilities and systems that will attract increased public and private investment in stroke research in Australia.
We encourage you to complete this 10 minute survey, and to distribute broadly within your networks. Please click here to start the survey.

Architecture contributes to positive health outcomes - Michelle Shannon

Architecture can contribute to positive health outcomes for people. However, which people and in what locations is health design research being applied? How can we adapt the built environment sustainably for an ageing population or for those people with chronic conditions? Read more... 

Circuit class therapy for improving mobility after stroke - Coralie English 

Roald Dahl wrote of his wife’s rehabilitation after stroke in 1965:
'Surely one hour a day is not enough?'
It was this exact same thought I had 30-odd years later as a new graduate physiotherapist that sparked my interest in research and led me down the path of researching different models of providing more therapy to people after stroke. Our recently published Cochrane review provides further robust evidence that group circuit class therapy improves walking ability after stroke. It may also help stroke survivors increase their daily physical activity and improve their fitness – both important factors for staying healthy and reducing risk of future stroke.  Read more... 

Collaboration, post-stroke fatigue & functional magnetic resonance imaging - Peter Goodin

In science, collaboration is key. Collaboration leads to discussion, which can lead to new ideas, discoveries or breakthroughs. Collaboration has the potential to allow us to see our field through new eyes and make connections where we were unable to see them before.
Recently, thanks to the collaboration between The Florey Institute of Neuroscience and Mental Health, the Hunter Medical Research Institute (HMRI), as part of the Centre for Research Excellence in Stroke Rehabilitation and Brain Recovery, and the generous support of the James S. McDonnell Foundation I was given the opportunity to apply an analysis method I developed to explore how brain regions connect to each other in post-stroke fatigue using functional magnetic resonance imaging (fMRI). Read more...

Twitter (@strokeCRE)

We reached a milestone this month on Twitter when we clocked up 1,000 followers. To keep abreast of stroke research across the globe follow the CRE on Twitter (@strokeCRE).

National Stroke Week

The Stroke Foundation's National Stroke Week is on from Monday 4 to Sunday 10 September. Will you join the F.A.S.T. Response Team and fight stroke with the Stroke Foundation this September?
Register here.

CRE Publications

Bernhardt J. Editorial. Int J Stroke. 2017;12(5):443-443.

Bernhardt J, Hayward KS, Kwakkel G, Ward NS, Wolf SL, Borschmann K, et al. Agreed definitions and a shared vision for new standards in stroke recovery research: The Stroke Recovery and Rehabilitation Roundtable taskforce. Int J Stroke. 2017;12(5):444-50.

Kwakkel G, Lannin NA, Borschmann K, English C, Ali M, Churilov L, et al. Standardized measurement of sensorimotor recovery in stroke trials: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable. Int J Stroke. 2017;12(5):451-61.

Corbett D, Carmichael ST, Murphy TH, Jones TA, Schwab ME, Jolkkonen J, et al. Enhancing the alignment of the preclinical and clinical stroke recovery research pipeline: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable translational working group. Int J Stroke. 2017;12(5):462-71.

Walker MF, Hoffmann TC, Brady MC, Dean CM, Eng JJ, Farrin AJ, et al. Improving the development, monitoring and reporting of stroke rehabilitation research: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable. Int J Stroke. 2017;12(5):472-9.

Boyd LA, Hayward KS, Ward NS, Stinear CM, Rosso C, Fisher RJ, et al. Biomarkers of stroke recovery: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable. Int J Stroke. 2017;12(5):480-93.

English C, Hillier SL, Lynch EA. Circuit class therapy for improving mobility after stroke. Cochrane Database of Systematic Reviews 2017, Issue 6. Art. No.: CD007513. DOI: 10.1002/14651858.CD007513.pub3

The ATTEND Collaborative Group. Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial. Lancet. 2017:1-12.

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Do you want to participate in research? Send us comments on our research? Want to join in CRE activities? Then stay on this mailing list.
Copyright © 2017 The Florey Institute of Neuroscience and Mental Health, All rights reserved.

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