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NEWSLETTER
May 2016

Upcoming events

 

June 13, 2016 

NARILIS SEMINAR by post-doc researcher Benjamin Le Calve

L12 auditorium, UNamur

12:45-13:45

Benjamin Le Calve recently joined the "Tumor Hypoxia" research group from Prof. Carine Michiels (URBC, UNamur). He will present his postdoctoral work performed at the Department of Biochemistry and Molecular Medicine of the University of Montréal, during a seminar entitled "Aberrant ERK signalling suppresses pancreatic cancer progression through the p21 induction".
 

June 14, 2016 

PhD thesis defense in Veterinary Sciences by Catherina Lensen

M01 auditorium, UNamur

14:00-16:00

"Behavioural and physiological parameters indicative of potential behaviour problems in dogs" (promoter: Claire Diederich)
More info

 

June 20, 2016 

Meeting of the Belgian Society of Biochemistry and Molecular Biology

Erasme Campus Anderlecht (ULB)

9:00-17:00

"New insights in Molecular Mechanisms of Neurodegeneration"
Posters presentations: all topics are welcome!

More info

News

NARILIS researcher Vanessa Colombaro wins award for Best Oral Presentation at the ERCSG meeting 2016

Vanessa Colombaro performed her PhD work at the Molecular Physiology Research Unit of UNamur, under the mentorship of Prof. Nathalie Caron. Two months ago, she successfully defended her doctoral thesis regarding the involvement of hyaluronan in the pathophysiology of renal ischemia-reperfusion injury.
During the 28th annual meeting of the European Renal Cell Study Group (ERCSG) which was held in April 2016 in Paris, Vanessa had the opportunity to present her work during the session dedicated to Acute Kidney Injury. This renowned conference brings together researchers from all over Europe to discuss the cellular, molecular and physiological aspects of renal cell biology with emphasis on models of the normal and the diseased kidney. With her talk entitled “Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation and fibrosis due to an accumulation of low molecular weight hyaluronan”, Vanessa won the prize for the Best Oral Presentation!

Best poster prize for NARILIS PhD student Marie-Ange Angladon at the Doctoral Interdisciplinary Training School 2016

Marie-Ange Angladon is a PhD student at the Department of Chemistry of UNamur, within the Laboratory of Physico-Chemical Informatics of Prof. Daniel Vercauteren. Her thesis research is directed towards the study of protein-lipids interactions using theoretical methods, and in particular aims at understanding the effect of membrane lipids on the structural and functional properties of the µ opioid receptor.
From May 17 to 19, Marie-Ange Angladon took part to the Doctoral Interdisciplinary Training School at the UNamur, and presented her research work during the poster session. Her poster entitled “Comparison of coarse-grain and all-atom methods for the study of the μ opioid receptor” was awarded with the prize from the academic jury and doctoral student jury.

New NARILIS research publications

Radiolabeled antibodies targeting endoglin: promising tools for cancer imaging and therapy
Prof. Stéphane Lucas is the Principal Investigator of THERAPLUS, a NARILIS project supported by the Walloon Region and which main objective is to improve radiation therapy. As part of the THERAPLUS project, a study was performed in collaboration with the Louvain Drug Research Institute of UCL to evaluate the in vivo stability of radiolabeled mAbs directed agains endoglin. Endoglin (CD105) is a membrane glycoprotein expressed on vascular endothelial cells and was shown to be a powerful marker of tumor angiogenesis. The use of radiolabeled mAbs directed against CD105 represents therefore a promising strategy for cancer imaging and therapy. In a recent publication, they present the comparative biodistribution data of directly and indirectly iodinated anti-CD105 mAbs in tumor-bearing mice.
Cost analysis of sentinel lymph node (SLN) biopsy in head and neck cancer
SLN biopsy offers a minimally invasive tool to evaluate the presence of regional metastases in head and neck cancers. In order to obtain precise estimates of the real costs of this approach, Prof. Bruno Krug from the CHU UCL Namur, Prof. Annick Castiaux from the UNamur and the Institute of Health and Society of UCL performed a cost calculation across all phases of a patient's care cycle of the SLN biopsy. This process involves the contribution of different departments from the CHU UCL Namur - Godinne, including the Nuclear Medicine Department for preoperative imaging (Prof. Bruno Krug), the Head and Neck Surgery Department for SLN biopsy (Prof. Georges Lawson) and the Histopathology Laboratory for pathological examination (Prof. Marie-Cécile Nollevaux). 
Medialization thyroplasty: using peak direct subglottic pressure as an objective measure to determine the optimal implant size
Medialization thyroplasty (MT) has become the treatment of choice for glottic insufficiency, but one of the challenges after MT is the persistence of symptoms due to incorrect implant size. The Otolaryngology, Head and Neck Surgery Department of the CHU UCL Namur - Godinne performed a prospective study to evaluate the use of peak direct subglottic pressure level as an objective measure to assist in the choice of the correct implant size during MT. Benoit Bihin, biostatistician at the NARILIS institute, carried out the statistical analysis on the data obtained from the 32 patients enrolled in this study. 
For further research news, please visit NARILIS website






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